Биология ва тиббиёт муаммолари 2025, №3.1 (162)


Subject of the article

МИГРЕН ПАТОГЕНЕЗИДА ЦИТОКИНЛАРНИНГ ЎРНИ (29-31)

Authors

Ахмедова Дилафрўз Баҳодировна

Institution

Бухоро давлат тиббиёт институти, Ўзбекистон Республикаси, Бухоро ш.

Abstract

Ушбу мақолада мигрен патогенезида цитокинларнинг ўрни таҳлил қилинган. Мигренда тригеминоваскуляр тизимнинг фаоллиги, нейроваскуляр яллиғланиш жараёнлари ва цитокинлар даражасининг ўзгариши муҳокама қилинган. TNF-α, IL-6, IL-1β каби прояллиғланиш цитокинларининг мигрен механизмидаги аҳамияти, уларнинг хуруж пайти ва хуруждан ташқари вақтдаги динамикаси кўриб чиқилган. Шунингдек, анти-CGRP терапияси ва иммунотерапиянинг янги ёндашувлари таҳлил қилинган.

Key words

мигрень, цитокинлар, тригеминоваскуляр тизим, IL-6, IL-1β, иммунотерапия.

Literature

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