Reproduktiv salomatlik va uro-nefrologik tadqiqotlar jurnali 2026 №2

Subject of the article

MUDDATIDAN OLDINGI TUG‘RUQ: XAVF OMILLARI VA PROFILAKTIKA STRATEGIYALARI (73-76)

Authors

Xamidova Shaxlo Musinovna, Xakimova Ruhshona Abduraxmonovna

Institution

Samarqand davlat tibbiyot universiteti

Abstract

Mazkur ilmiy maqolada muddatidan oldingi tug‘ruq (MOT) muammosining zamonaviy akusherlikdagi dolzarbligi tahlil qilinadi. Muddatidan oldin tug‘ruq ona va perinatal kasallanish hamda o‘lim ko‘rsatkichlarini oshiruvchi asosiy omillardan biri bo‘lib, uning kelib chiqishi ko‘p omilli patogenezga ega. Maqolada muddatidan oldin tug‘ruq rivojlanishiga olib keluvchi asosiy xavf omillari - infektsion yallig‘lanish jarayonlari, bachadon bo‘yni yetishmovchiligi, ko‘p homilalik, ekstragenital kasalliklar, psixosomatik stress va ijtimoiy omillar keng yoritilgan. Shuningdek, muddatidan oldin tug‘ruqni oldini olishda qo‘llaniladigan zamonaviy profilaktika strategiyalari, jumladan, skrining va risk-stratifikatsiya, progesteron terapiyasi, servikal serklyaj, pessar qo‘llash, infeksiyalarni erta aniqlash va davolash, shuningdek, hayot tarzini optimallashtirishning klinik ahamiyati asoslab berilgan. Ilmiy dalillarga asoslangan multidisiplinar yondashuv muddatidan oldin tug‘ruqning oldini olish va perinatal natijalarni yaxshilashda hal qiluvchi omil sifatida ko‘rsatiladi.

Key words

muddatidan oldingi tug‘ruq, perinatal xavf, risk omillari, bachadon bo‘yni yetishmovchiligi, progesteron, serklyaj, pessar, infeksiya, profilaktika, skrining.

Literature

1. World Health Organization. (2023). Preterm birth: Key facts and global burden. WHO publications. 2. Blencowe H, Cousens S, Oestergaard M.Z. National, regional, and worldwide estimates of preterm birth rates // The Lancet. – 2012. – Т. 379. – №. 9832. – С. 2162–2172. 3. Chawanpaiboon S., Vogel J.P., Moller A.B., et al.Global, regional, and national estimates of levels of preterm birth in 2014 // The lancet global health. – 2019. – Т. 7. – №. 1. – С. e37–e46. 4. Goldenberg R.L., Culhane J.F., Iams J.D., Romero R. Epidemiology and causes of preterm birth // The Lancet. – 2008. – Т. 371. – №. 9606. – С. 75–84. 5. Romero R., Dey S.K., Fisher S.J. Preterm labor: one syndrome, many causes // Science. – 2014. – Т. 345. – №. 6198. – С. 760–765. 6. Muglia L.J., Katz M. The enigma of spontaneous preterm birth // New England Journal of Medicine. – 2010. – Т. 362. – №. 6. – С. 529– 535. 7. Iams J.D., Goldenberg R.L., Meis P.J., et al. The length of the cervix and the risk of spontaneous preMOTure delivery // New England Journal of Medicine. – 1996. – Т. 334. – №. 9. – С. 567–572. 8. Berghella V. Cervical assessment by ultrasound for preventing preterm delivery // Cochrane Database of SysteMOTic Reviews. – 2013. – №. 1. 9. Conde-Agudelo A., Romero R. Vaginal progesterone to prevent preterm birth in women with a short cervix // American Journal of Obstetrics & Gynecology. – 2016. – Т. 214. – №. 1. – С. 1–17. 10. Meis P.J., Klebanoff M., Thom E., et al. Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate // New England Journal of Medicine. – 2003. – Т. 348. – №. 24. – С. 2379–2385. 11. Hassan S.S., Romero R., Vidyadhari D., et al. Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix // Ultrasound in Obstetrics & Gynecology. – 2011. – Т. 38. – №. 1. – С. 18–31.