Журнал кардиореспираторных исследований 2025. №2/2
Maqola mavzusi
MIKRORNK BIOMARKERINING BUYRAK SHIKASTLANISHIDAGI DIAGNOSTIK AHAMIYATI (61-64)
Mualliflar
Xamrayev Xamza Xamidullayevich, Sultonov Ilhom Islomovich, Husinov Akobir Azamovich, Normuradov Alisher Ismoilovich
Muassasa
Samarqand davlat tibbiyot universiteti
Annotatsiya
Rezyume: Ushbu maqolada mikroRNK buyrak shikastlanishining istiqbolli biomarkerlari sifatida roli ko‘rib chiqiladi. An’anaviy laboratoriya markerlari, masalan, kreatinin va siydik mochevinasi, patologik o‘zgarishlarni erta bosqichda aniqlash imkonini bermaydi. Shu sababli, yallig‘lanish, fibroz va apoptoz kabi jarayonlarni tartibga soluvchi mikroRNKlar istiqbolli diagnostika vositalari sifatida qaralmoqda. Qon va siydikdagi ma’lum mikroRNK darajalarini tahlil qilish buyrak shikastlanishini erta aniqlash va kasallik rivojlanishini bashorat qilishga yordam berishi mumkin. Ushbu sohada keyingi tadqiqotlar usullarni standartlashtirish va klinik amaliyotga joriy etish uchun zarurdir.
Kalit so'zlar
mikroRNK, biomarkerlar, buyrak shikastlanishi, diagnostika, molekulyar usullar
Adabiyotlar
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