Reproduktiv salomatlik va uro-nefrologik tadqiqotlar jurnali 2026 №2

Тема статьи

AUTOIMMUNE THYROIDITIS AND PREGNANCY (82-86)

Авторы

Kamalova Dilafruz Doniyorovna

Учреждение

Samarkand State Medical University

Аннотация

Autoimmune thyroiditis is one of the most common endocrine diseases of women of reproductive age and an important clinical issue during pregnancy. Characterised by immune-mediated dysfunction of the thyroid gland and the detection of autoantibodies against thyroid gland structures, this condition may be asymptomatic or develop some biochemical changes that become of clinical importance in the face of increased physiological demands of gestation. Even in euthyroid women, thyroid autoimmunity has been linked to adverse obstetric and neonatal outcomes, so it is important to conduct careful evaluation and monitoring. This study was carried out in order to determine the extent to which autoimmune thyroiditis affected the course of pregnancy and perinatal effects with special reference to maternal thyroid function dynamics and foetal adaptation. A method of observational clinical management was adopted, which included regular antenatal and endocrine evaluation. Maternal thyroid function tests, antibody status, pregnancy complications and neonatal outcomes were analysed to look for patterns having a clinical meaning. The results showed that autoimmune thyroiditis is linked to a higher risk of pregnancy complications, such as threatened miscarriage, premature delivery and growth restriction of the foetus, especially in women who developed hypothyroidism during pregnancy. Neonatal outcomes showed an increased incidence of low-birth weight and increased neonatal intensive care requirement in the pregnancies when the mother had a thyroid dysfunction.

Ключевые слова

Autoimmune Thyroiditis Pregnancy Complications Hypothyroidism, Thyroid auto antibodies, Perinatal Outcome

Литературы

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