Биология ва тиббиёт муаммолари 2025, №4 (163)

Subject of the article

ОСОБЕННОСТИ ВАРИАБЕЛЬНОСТИ КИШЕЧНОЙ МИКРОБИОТЫ У ДЕТЕЙ ПРИ НЕИНФЕКЦИОННЫХ ЗАБОЛЕВАНИЯХ ЖЕЛУДОЧНО-КИШЕЧНОГО ТРАКТА (376-385)

Authors

Турдиева Шохида Толкуновна, Насирова Гулмира Рамзитдиновна

Institution

Ташкентский государственный медицинский университет, Республика Узбекистан, г. Ташкент

Abstract

Данная статья посвящена актуальной проблеме — особенностям изменчивости кишечной микробиоты у детей при патологии желудочно-кишечного тракта (ЖКТ) неинфекционного генеза, что представляет собой одно из приоритетных направлений современной детской гастроэнтерологии. Несмотря на важность микробиоты как интегрального звена гомеостаза, в практической педиатрии её роль при терапии таких заболеваний часто недооценивается, особенно при назначении медикаментозных препаратов. Это нередко приводит к развитию функ-циональных нарушений кишечника, ошибочно расцениваемых как самостоятельная патология. В ходе работы проанализировано свыше 200 публикаций отечественных и зарубежных исследователей за последние 10 лет, посвящённых динамике и клиническим аспектам микробиоты кишечника у детей с неинфекционными заболеваниями ЖКТ различного происхождения. Особое внимание уделено патогенетическим механизмам, влиянию фармакологических агентов на микробный пейзаж.

Key words

пробиотики, микробиота кишечника, дети, функциональные нарушения, запор, пребиотики.

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