Биология ва тиббиёт муаммолари 2023 №5 (148)


Subject of the article

EVALUATION OF THE EFFECTIVENESS OF THE USE OF SUBTHRESHOLD MICROPULSE LASER EXPOSURE IN THE TREATMENT OF DIABETIC MACULAR EDEMA (286-288)

Authors

Yangieva Nodira Rakhimovna, Giyasova Akida Orifkhonovna

Institution

1 - Tashkent State Dental Institute, Republic of Uzbekistan, Tashkent; 2 - "SIHAT KO'Z" LTD Joint Venture, Republic of Uzbekistan, Tashkent

Abstract

Diabetic macular edema (DME) is the most common cause of visual impairment in patients with diabetes mellitus (DM) and can occur at any stage of diabetic retinopathy. The prognosis of the visual functions of the organ of vision is unfavorable, in the absence of timely treatment of intraocular complications of DM. Subthreshold micropulse laser exposure (SMPLE) 577nm is a safe and reproducible method for the treatment of DME, which can be applied in real clinical conditions using fixed parameters and protocols. This study examined the visual and anatomical results of 577 nm micropulse laser photocoagulation in previously untreated DME eyes at 12 months.

Key words

diabetic macular edema, subthreshold micropulse laser exposure, optical coherence tomography.

Literature

1. Bobykin E.V. Modern approaches to the treatment of diabetic macular edema. Ophthalmosurgery. 2019. No. 1. P. 67-76. [In Russ.]. 2. Distefano L.N., et al. Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review. J. Ophthalmol. 2017:2407037. 3. Doga A.V., et al. Comparative study of the effectiveness and safety of the technology of combined laser exposure and traditional laser coagulation in the treatment of diabetic macular edema. Diabetes. 2017;20(1):68-74. [In Russ.]. 4. Figueira J., et al. Prospective randimized con-trolled trial comparing sub-threshold micropulse diode laser photocoagulation and conventional green laser for clinically significant diabetic macular oedema. Br. J. Ophthalmol, 2009, vol. 93, pp. 1341–1314. 5. Fokin V. P., et al. Analysis of the effectiveness of a combined treatment method for diabetic macular edema. Vestnik NSU. Series: Biology, clinical medicine. 2011. Vol. 9. Issue. 4. S. 43-47. [In Russ.]. 6. Friberg TR, et al. The treatment of macular dis-ease using a micropulsed and continuous wave 810-nm diode laser. Ophthalmology 1997; 2030–2038. 7. Ibragimova, R. R. Promising directions of pathogenetic treatment of diabetic retinopathy and diabetic macular edema // Medical Bulletin of Bashkortostan. - 2020. - T. 15, No. 4 (88). - pp. 108-112. [In Russ.]. 8. Kirilyuk, M. L. et al. Pathogenesis of diabetic retinopathy: a review of the literature // In-ternational Journal of Endocrinology. - 2019. - V. 15, No. 7. - S. 567-575. [In Russ.]. 9. Moisseiev E, et al. Subthreshold micropulse laser reduces anti-VEGF injection burden in patients with diabetic macular edema. Eur J Ophthalmol. 2018;28:68–73. 10. Pankratov MM. Pulsed delivery of laser energy in experimental thermal retinal photocoagulation. Proc Soc Photo Opt Instrum Eng. 1990;1202:205–13. 11. Schmidt-Erfurth U. et al. Guidelines for the management of diabetic macular edema by the European Society of Retina Specialists (EURETINA). Ophthalmologica. 2017;237(4): 185-222. 12. Shaya F.T., Aljawadi M. Diabetic retinopathy. Clin Ophthalmol. 2007;1(3); 259-265. 13. Vorontsova T.N. Possibilities of using a diode laser in diseases of the retina in children. Ophthalmological records. 2008. No. 1. S. 24-28. [In Russ.]