Журнал кардиореспираторных исследований. Special Issue 1.1.(сборник статей)
Subject of the article
GIPERTONIYA KASALLIGI BILAN BEMORLARDA ARTERIAL QON BOSIMI KUNLIK PROFILI KO’RSATKICHLARIGA SELEKTIV BETA-ADRENOBLOKATORLARNING TA’SIRINI BAHOLASH (84-87)
Authors
S.Kh. Yarmuxamedova., Sh.A. Amirova
Institution
Samarqand davlat tibbiyot universiteti
Abstract
Davolashdan oldin va keyin bisoprolol bilan terapiya paytida AQBSMda ijobiy tendentsiya kuzatildi. Bisoprolol bilan 12 haftalik davolanishdan so’ng, ofis o’lchovlarida maqsadli qon bosimi darajasi (140/90 mm Hg dan kam) 16 kishiga (26%) erishildi. Maqsadli qon bosimiga erisha olmagan 9 bemorda, ofisda o’lchanganida, o’tirgan holatda o’rtacha AQB 10 mm Hg ga kamaydi. Qon bosimini ofis o’lchash natijalariga ko’ra, bisoprolol bilan davolash natijasida o’rganilayotgan bemorlar guruhida sistolik va diastolik qon bosimining sezilarli darajada pasayishiga erishildi. Sutkalik qon bosimi monitoringining dastlabki ma’lumotlarini tahlil qilish imkon berdi. Sistolik va diastolik qon bosimining o’rtacha sutkalik, o’rtacha kunlik va o’rtacha tungi qiymatlarining oshishi, kunlik qon bosimi profilining buzilishini aniqlash. Beta-blokator bisoprolol AG II darajasi bilan bemorlarni davolashda yuqori klinik samaradorlikka ega. Bisoprolol bilan 12 haftalik terapiya qon bosimining maqsadli darajasini saqlab qolish, kunduzi va kechasi qon bosimining o’zgaruvchanligini kamaytirish, sistolik va diastolik qon bosimining tungi pasayish darajasini normallashtirish imkonini beradi. Shuning uchun, gipertoniya bilan og’rigan bemorlarda bisoprolol 12 hafta davomida sistolik va diastolik qon bosimining o’rtacha qiymatlarining pasayishini, shuningdek, kunduzi va kechasi qon bosimining o’zgaruvchanligini ta’minlaydi
Key words
Arterial qon bosimining sutkalik monitoringi, bisoprolol, AQB o’zgaruvchanligi (variabelligi), sistolik va diastolik qon bosimining o’rtacha sutkalik, o’rtacha kunlik va o’rtacha tungi qiymatlari.
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