Biomeditsina va amaliyot jurnali, 2022 №6

Subject of the article

ANALYSIS OF FACTORS PREDISPOSITIONING TO THE DEVELOPMENT OF CONGENITAL MALFORMATIONS OF THE MAXILLOFACIAL REGION (286-294)

Authors

Gulmukhamedov B. Pulat, Rizaev A. Jasur, Khabilov L. Nigman, Boboev T. Kodirzhon

Institution

Samarkand State Medical University

Abstract

The analysis of literary sources showed a variety of causal factors contributing to the development of congenital malformations of the maxillofacial region (CMMFR), among which there are exogenous (smoking, alcohol consumption, exposure to drugs, insecticides, stress, etc.) and endogenous agents (hereditary predisposition, genetic component). The relationship between the above causal factors and the birth of children with CMMFR determines the urgent need for their timely identification by the relevant specialists when working with couples. In addition, targeted advisory and preventive work carried out at the early stages of pregnancy planning will prevent and significantly reduce the risk of having children with various forms of malformations

Key words

CMMFR, cleft lip, cleft palate, exogenous factors, endogenous factors, association.

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