Kardiorespirator tadqiqotlar jurnali. Maxsus son. 2022
Subject of the article
O’PKANING SURUNKALI OBSTRUKTIV KASALLIGIDA O’PKA ARTERIYASIDAGI SISTOLIK QON BOSIMI DARAJASINI O’NG QORINCHA FUNKSIONAL KO’RSATKICHLARIGA TA’SIRI (324-328)
Authors
Yarmatov S.T.
Institution
Samarqand Davlat Tibbiyot Universiteti
Abstract
Butun jahonda, shu jumladan, respublikamizda ekologik vaziyatning yomonlashuvi oqibatida nafas olish tizimi kasalliklariga chalingan bemorlar soni ko‘payib bormoqda. Rasmiy ma’lumotlarga qaraganda, O‘zbekistonda nafas olish tizimi kasalliklari birinchilar qatorida turadi. Keyingi 10-15 yillar ichida surunkali o‘pka kasalliklariga chalingan bemorlar soni uch baravarga oshgan. O‘lim ko‘rsatgichi bo‘yicha esa nafas olish tizimi kasalliklari yurak qon-tomir kasalliklaridan keyingi o‘rinni egallab kelmoqda. O‘pkaning surunkali obstruktiv kasalligi yig‘ma tushuncha bo‘lib, o‘zida surunkali obstruktiv bronxit va o‘pka emfizemasini birlashtiradi. So'nggi yillarda O’SOK bilan og'rigan bemorlarda kasallanish, erta nogironlik va o'lim dinamikasi salbiyligicha qolmoqda. O'lim sabablari orasida O’SOK barcha nafas olish tizimi a’zolari kasalliklaridan o’limning 85% ni tashkil qiladi. O’SOKda erta nogironlik va o'limning asosiy sabablaridan biri nafas yetishmovchiligi va o'ng qorincha (O’Q) yetishmovchiligining dekompensatsiyasiga olib keladigan dekompensatsiyasining rivojlanishida an'anaviy ravishda o'pka gipertenziyasi (O’G) muhim rol o'ynaydi. O’SOK bilan og'rigan bemorlarda O’G shakllanishi qon tomir devoridagi proliferatsiyaga bog’liq struktur o'zgarishlar, silliq mushak hujayralarining migratsiyasi, fibroelastoz, adventisiyaning qalinlashishi natijasida yuzaga keladi. O'pka mikrosirkulyatsiyasining buzilishlari asosida ventilyatsiyion-perfuzion nisbatning buzilishi, o’pka gipertenziyasi shakllanish va rivojlanishida endoteliyning funksional faolligidagi buzilishlar yotadi. Ko'pgina mualliflar O’SOK bilan og'rigan bemorlarda O’G darajasi yuqori ekanligini ta'kidlaydilar. Butun jahonda, shu jumladan, respublikamizda ekologik vaziyatning yomonlashuvi oqibatida nafas olish tizimi kasalliklariga chalingan bemorlar soni ko‘payib bormoqda. Rasmiy ma’lumotlarga qaraganda, O‘zbekistonda nafas olish tizimi kasalliklari birinchilar qatorida turadi. Keyingi 10-15 yillar ichida surunkali o‘pka kasalliklariga chalingan bemorlar soni uch baravarga oshgan. O‘lim ko‘rsatgichi bo‘yicha esa nafas olish tizimi kasalliklari yurak qon-tomir kasalliklaridan keyingi o‘rinni egallab kelmoqda. O‘pkaning surunkali obstruktiv kasalligi yig‘ma tushuncha bo‘lib, o‘zida surunkali obstruktiv bronxit va o‘pka emfizemasini birlashtiradi.
Key words
o’pka gipertenziyasi, o’pkaning surunkali obstruktiv kasalligi, surunkali o’pka-yurak, o’pka arteriyasida sistolik qon bosimi, birlamchi o’pka gipertenziyasi.
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