Doktor axborotnomasi 2022, №4 (108)
Subject of the article
NEUROLOGICAL MANIFESTATIONS AND COMPLICATIONS IN PATIENTS WITH CORONAVIRUS INFECTION (154-160)
Authors
U. Z. Isametdinova
Institution
Samarkand state medical university, Samarkand, Uzbekistan
Abstract
It is becoming clear that the neurological complications of COVID-19 are very common, but in some cases it is difficult to establish a causal relationship. For example, stroke may occur for reasons unrelated to coronavirus infection, while Guillain-Barré syndrome and meningoencephalitis are likely to be parainfectious. Only long-term epidemiological studies in large groups of patients allow to clarify some of these issues. This study helps to understand better the mechanisms of development of complications and develop schemes for their treatment and subsequent rehabilitation. The article presents the mechanisms of penetration of the coronavirus into the nervous system and systematizes the neurological manifestations and complications of COVID-19, which were described in the first 18 months of the pandemic. Particular attention is paid to the complications of COVID-19 in the central and peripheral nervous system, the most interesting clinical examples are given. Summing up the analysis of the literature, we can say that the clinical picture of neurological diseases and syndromes caused by coronavirus infection corresponds to the usual ideas. We also considered the assumption that SARS-CoV-2 can persist in the central nervous system for a long time in the form of inactive fragments, which means that it can recur in predisposed individuals when appropriate conditions arise. This assumption raises concerns regarding to long-term neurological complications in infected and cured patients.
Key words
stroke, neurological complications of COVID-19, acute myelitis, Guillain-Barré syndrome, encephalitis, COVID-19.
Literature
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