Журнал кардиореспираторных исследований 2025. №2/1

Maqola mavzusi

Yurak ishemik kasalligi bilan og‘rigan bemorlarda klinik-asbobiy ma’lumotlar asosida miokard revaskulyarizatsiyasi samaradorligini baholash (11-16)

Mualliflar

M.D. Abdulloeva, D.O. Rasulova

Muassasa

Samarqand Davlat Tibbiyot Universiteti

Annotatsiya

Tadqiqot maqsadi yurak ishemik kasalligi bilan og'rigan bemorlarda miokard revaskulyarizatsiyasining turli usullarining samaradorligini kompleks klinik, instrumental, funktsional va biokimyoviy baholashni o'tkazish, shuningdek, yurak-qon tomir asoratlari rivojlanishining bashorat qiluvchi omillarini aniqlash. Materiallar va usullar. Tadqiqotga yurak ishemik kasalligi bilan og'rigan va rejali miokard revaskulyarizatsiyasidan o'tgan 96 bemor kiritilgan. Aralashuv usuliga qarab, bemorlar ikki guruhga bo'lingan: I guruh (n = 52) — perkutan koronar aralashuvdan (PCI) so'ng, II guruh (n = 44) — koronar arteriya bypass payvandlashdan (CABG) so'ng. Elektrokardiografik va ekokardiografik parametrlarning dinamikasi, troponin I va CPK- MB darajalari, lipid profil parametrlari, asoratlar darajasi va SF-36 va KCCQ shkalalari yordamida hayot sifati baholandi. Statistik tahlil SPSS 26.0 paketi yordamida Student t-testi va χ² mezonidan foydalangan holda amalga oshirildi; farqlar p < 0,05 da statistik jihatdan ahamiyatli deb hisoblandi. Natijalar. Aralashuvdan olti oy o'tgach, klinik va instrumental parametrlarda sezilarli yaxshilanish kuzatildi: chap qorincha chiqarish fraksiyasining o'rtacha 12% ga oshishi, EKGda ishemik o'zgarishlarning chastotasi 3 martadan ko'proqqa kamaydi. PCI dan keyin bemorlarning 83% da va CABG dan keyin 89% da to'liq revaskulyarizatsiyaga erishildi. Asoratlar darajasi mos ravishda 32,7% va 50,0% ni tashkil etdi. Noqulay natijalarning asosiy bashorat qiluvchi omillari chap qorincha chiqarish fraksiyasining 45% dan pastga pasayishi, troponin I darajasining 0,5 ng/ml dan ortiqqa oshishi, 2-toifa diabet va NYHA ma'lumotlariga ko'ra III-IV funktsional sinfdagi surunkali yurak yetishmovchiligining mavjudligi ekanligi aniqlandi. Hayot sifati ko'rsatkichlari sezilarli darajada yaxshilandi: SF-36 umumiy balli 48,5 dan 74,5 gacha, KCCQ shkalasi balli - 49,3 dan 77,9 gacha oshdi (p < 0,001). Xulosa. Koronar arteriya kasalligi bilan og'rigan bemorlarda miokard revaskulyarizatsiyasi miokard qisqarish qobiliyati va hayot sifatining sezilarli darajada yaxshilanishi bilan bog'liq. Teri orqali aralashuvlar tezroq funktsional tiklanishni ta'minlaydi, koronar arteriyani bypass payvandlash esa uzoq muddat davomida barqarorroq gemodinamik ta'sir bilan tavsiflanadi. Aniqlangan xavf omillari bemorlarni optimallashtirish va yurak-qon tomir asoratlari chastotasini kamaytirish imkonini beradi.

Kalit so'zlar

ishemik yurak kasalligi, miokard revaskulyarizatsiyasi, perkutan koronar aralashuv, koronar arteriyani shuntlash, asoratlar, troponin I, ejeksiya fraksiyasi, hayot sifati

Adabiyotlar

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