Биология ва тиббиёт муаммолари 2025, №4 (163)

Maqola mavzusi

CHALLENGES IN THE INITIAL DIAGNOSIS OF BRAIN TUMORS: A RETROSPECTIVE ANALYSIS (131-134)

Mualliflar

Murodova Dilorom Subhonovna, Polatova Jamilya Shagairatovna, Kariev Shukhrat Maratovich, Alimov Ijod Rustamjonovich, Khazratkulov Rustam Bafoevich

Muassasa

1 - Center for the development of professional qualifications of medical workers, Republic of Uzbekistan, Tashkent; 2 - Scientific and Practical Center for Pediatric Hematology, Oncology and Clinical Immunology, Ministry of Health of the Republic of Uzbekistan, Tashkent; 3 - Republican Specialized Scientific and Practical Medical Center for Neurosurgery, Ministry of Health of the Republic of Uzbekistan, Tashkent

Annotatsiya

Objective: To evaluate the timeliness and effectiveness of the initial diagnostic approach to patients with brain tumors in a regional healthcare setting. Methods: A retrospective cohort study was conducted including 147 patients diagnosed with brain tumors in Nano medical clinic and Neuron medical center, Uzbekistan, from 2022 to 2025. Patients were categorized based on histopathology into low-grade gliomas (LGG, n=37), high-grade gliomas (HGG, n=64), and meningiomas (n=46). Time intervals from symptom onset to medical consultation, imaging, and surgery were analyzed. Results: Median time from symptom onset to specialist consultation ranged between 3–6 days, varying by tumor type. Early consultation was more common among patients presenting with seizures or paresis (>85%) than headaches (<30%). MRI was self-initiated in 13.5–21.6% of cases. A significant portion (37.4%) received symptomatic treatment without referral for imaging. Delays in MRI and surgery were prominent, especially in meningioma cases (median 248 days from symptom onset to surgery). Conclusion: Despite advanced neuroimaging availability, delays in diagnosis and treatment persist. Increasing clinical awareness and optimizing referral pathways are essential for improving timely diagnosis and outcomes.

Kalit so'zlar

Brain tumor diagnosis, Diagnostic delay, Neuroimaging, Treatment barriers.

Adabiyotlar

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