Журнал кардиореспираторных исследований 2026. №2/3

Тема статьи

Modern immunopathogenetic mechanisms of rheumatoid arthritis (67-71)

Авторы

M.S. Ravshanova, M.A. Eshbekov, Kh.I. Ibragimov, Sh.X. Ziyadullaev

Учреждение

Samarkand State Medical University

Аннотация

The immunological changes observed in RA provide crucial insights into the underlying mechanisms of disease development and progression. Autoantibodies, such as antibodies to rheumatoid factor (RF) and antibodies to cyclic citrullinated peptide (anti-CCP), play a key role in the pathogenesis of RA, contributing to inflammation and joint damage. Dysregulation of T cells, especially pro-inflammatory subpopulations, further contributes to the abnormal immune response seen in RA. Immunological changes observed in RA have important implications for prevention, early diagnosis, treatment and prognosis of the disease.

Ключевые слова

Rheumatoid arthritis, autoantibodies, pathogenesis, cytokines.

Литературы

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