Биология ва тиббиёт муаммолари 2025 №5 (165)

Тема статьи

CARDIAC REHABILITATION AS A KEY STAGE IN THE MANAGEMENT OF PATIENTS AFTER PERCUTANEOUS CORONARY INTERVENTION FOR MYOCARDIAL INFARCTION (110-115)

Авторы

Ismati Nigina Odilovna, Nasyrova Zarina Akbarovna

Учреждение

1 - Samarkand Regional Branch of the Republican Scientific and Practical Center of Cardiology, Republic of Uzbekistan, Samarkand; 2 - Samarkand State Medical University, Republic of Uzbekistan, Samarkand

Аннотация

The aim of the study is to evaluate the effectiveness of structured cardiac rehabilitation as a key stage in managing patients after primary percutaneous coronary intervention for acute myocardial infarction and to determine its impact on functional recovery, quality of life, and adherence to therapy. Materials and methods: A prospective comparative study included 80 patients aged 40-75 who had experienced a myocardial infarction with PCI performed within the first 24 hours of symptom onset, observed at the Samarkand branch of the Cardiology Center in 2024-2025. Patients were randomized: the rehabilitation group (n=40) underwent a 12-week structured program of exercise therapy, dietary and psychological support, secondary prevention, and monitoring of clinical parameters; the control group (n=40) received standard recommendations. Results: In the rehabilitation group, functional indicators improved significantly: the 6-minute walking distance increased from 358±68 to 442±71 m (p<0.001); MET increased from 4.1±0.7 to 5.8±1.0; VO2max - from 19.5±3.3 to 24.7±3.9 ml/kg/min (p<0.001). Quality of life improved according to MacNew and HADS (physical component from 4.1 to 5.3, p<0.001; anxiety - from 10.2 to 6.4, depression - from 9.8 to 6.1, p<0.001). Adherence to therapy increased (Morisky-Green score from 2.8±1.1 to 4.3±0.9; proportion with high compliance - from 34.3% to 72.1%, p<0.001). The frequency of recurrent MI, hospitalizations, and rhythm disturbances was significantly lower in the rehabilitation group. Conclusion: A comprehensive cardiac rehabilitation program significantly improves functional capacity, quality of life, adherence to therapy, and reduces the risk of adverse clinical outcomes in patients after PCI for myocardial infarction.

Ключевые слова

quality of life, psycho-emotional state, cardiac rehabilitation, myocardial infarction, adherence to therapy, psychological adaptation.

Литературы

1. List of used literature:Anderson LJ, Taylor RS. Cardiac rehabilitation for people with heart disease: an overview of Cochrane systematic reviews. Int J Cardiol. 2014;177(2):348–361. 2. Anderson L, et al. Exercise based cardiac rehabilitation for coronary heart disease. Cochrane Database Syst Rev. 2016;(1):CD001800. 3. Campos HO et al. Exercise based cardiac rehabilitation after myocardial revascularization: a systematic review and meta analysis. Rev Cardiovasc Med. 2022;23(2):074. 4. Adam CA et al. Exercise Training and Cardiac Rehabilitation in Patients After Percutaneous Coronary Intervention: Comprehensive Assessment and Prescription. J Clin Med. 2025;14(5):1607. 5. Bao X, Hong W, Feng L. Effects of Exer-cise Based Cardiac Rehabilitation on Patients Un-dergoing Percutaneous Coronary Intervention: A Systematic Review and Meta Analysis. Heart Surg Forum. 2024;27(7) E828–E837. ResearchGate+6journal.hsforum.com+6MDPI+6 6. Dibben G, Faulkner J, Oldridge N, et al. Exercise-based cardiac rehabilitation for coronary heart disease: updated Cochrane review. Cochrane Database Syst Rev. 2021;(11):CD001800. DOI:10.1002/14651858.CD001800.pub4 cochranelibrary.com+7PubMed+7PubMed+7 7. Osailan A, Abdelbasset WK. Exercise-based cardiac rehabilitation for post CABG patients using Incremental Shuttle Walking Test. J Saudi Heart Assoc. 2020;32(1):6. DOI:10.37616/2212 5043.1005 ResearchGate+1PMC+1 8. Rizaev J.A. et al. The importance of comorbid conditions in the development of chronic heart failure in elderly and senile patients // Achievements of science and education. - 2022. - No. 1 (81). - P. 75-79 (in Rus). 9. Rizaev J.A., Agababyan I. R. The relationship between periodontal diseases and acute coronary syndrome (literature review) // Journal of Biomedicine and Practice. - 2022. - Vol. 7. - No. 4. - P. 252 (in Rus). 10. Taylor RS et al. Home based versus centre based cardiac rehabilitation. Cochrane Database Syst Rev. 2014;(1):CD007130. Pub-Med+2PubMed+2American College of Cardiology+2 11. Oldridge N. Exercise based cardiac rehabilitation in patients with coronary heart disease: meta analysis outcomes revisited. Future Cardiol. 2012;8(6):729 751. 12. Safdar B, et al. Sex differences in response to a 12 week resistance training after cardiac surgery. Clin Ther. 2025;47(1):2529 2539. (см. стр. 2533, 2535) ahajournals.org 13. Mendes M, et al. Quality of life and functional capacity after cardiac surgery: ICU patients. World J Cardiol. 2024;16(8):436 447. ahajournals.org 14. Travensolo M, et al. TLiterature review on cardiac rehabilitation in CABG and PCI patients. APICare Online. 2021;7(2):1383–1394. 15. Rivas Estany E, Campos VA. Comprehensive CR reduces mortality and hospital admissions post PCI. Remedy Publ. 2018;1(2297):e pub pages 3 10