Biomeditsina va amaliyot jurnali, 2022 №6

Тема статьи



Djalalova M. Feruza.


Andijan State Medical Institute


One of the most urgent problems today is the problem of early diagnosis of non-invasive ductal carcinoma. Diagnostic and therapeutic tactics in NIPK is largely uncertain, since in many cases the tumor is characterized by a harmless course. The use of the screening algorithm for intraductal breast formations developed during the study allows optimizing the tactics of managing patients and predicting the outcomes of the disease.

Ключевые слова

ultrasound screening, diagnostics, intraductal formations


Abba MC, Gong T, Lu Y, Lee J, Zhong Y, Lacunza E, et al. A molecular portrait of high-grade ductal carcinoma in situ. Cancer Res (2015) 75:3980–90. 10.1158/0008-5472.CAN-15-0506 [PMC free article] [PubMed] [CrossRef] [Google Scholar] 2. Adams S, Gray RJ, Demaria S, et al. Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199. J Clin Oncol 2014; 32:2959–66. [PMC free article] [PubMed] [Google Scholar] 3. Afghahi A, Forgo E, Mitani AA, Desai M, Varma S, Seto T, et al. Chromosomal copy number alterations for associations of ductal carcinoma in situ with invasive breast cancer. Breast Cancer Res (2015) 17:108. 10.1186/s13058-015-0623-y [PMC free article] [PubMed] [CrossRef] [Google Scholar] 4. Fabienne Schwab, Katharina Redling, Matthias Siebert, Andy Schötzau.Cora- Annchoenenberger, Rosanna Zanetti-Dällenbach. Inter- and Intra-Observer Agreement in Ultrasound BI-RADS Classification and Real-Time Elastography Tsukuba Score Assessment of Breast Lesions// ultrasound in medicine in biology. volume 42, issue 11, p2622-2629, November 01, 2016/ Published: August 05, 2016 5. Fackler MJ, McVeigh M, Evron E, Garrett E, Mehrotra J, Polyak K, et al. DNA methylation of RASSF1A, HIN-1, RAR-beta, cyclin D2 and twist in in situ and invasive lobular breast carcinoma. Int J Cancer (2003) 107:970–5. 10.1002/ijc.11508 [PubMed] [CrossRef] [Google Scholar] 6. Krammer J, Pinker-Domenig K, Robson ME, Gonen M, Bernard-Davila B, Morris EA, et al.Breast cancer detection and tumor characteristics in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat. 2017;163(3):565–71. [PMC free article] [PubMed] [CrossRef] 7. Sweldens C, Peeters S, van Limbergen E, Janssen H, Laenen A, Patil S, et al. Local relapse after breast-conserving therapy for ductal carcinoma in situ: a European single-center experience and external validation of the Memorial Sloan-Kettering Cancer Center DCIS nomogram. Cancer J (2014) 20:1–7. 10.1097/PPO.0000000000000025 [PubMed] [CrossRef] [Google Scholar] 8. Tabar L, Vitak B, Chen TH, Yen AM, Cohen A, Tot T, et al. Swedish two-county trial: impact of mammographic screening on breast cancer mortality during 3 decades. radiology. 2011;260(3):658–63. [PubMed][CrossRef] 9. Tagliafico AS, Calabrese M, Mariscotti G, Durando M, Tosto S, Monetti F, et al. Adjunct screening with tomosynthesis or ultrasound in women with mammography-negative dense breasts: interim report of a prospective comparative trial. J Clin Oncol. 2016; [pubmed] 10. Tamimi RM, Baer HJ, Marotti J, Galan M, Galaburda L, Fu Y, et al. Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer. Breast Cancer Res (2008) 10:R67. 10.1186/bcr2128 [PMC free article] [PubMed] [CrossRef] [Google Scholar] 11. Shakhanova Shakhnoza, Rakhimov Nodir, Zaripova Parvina. Breast tumors in adolescent girls // Journal of Biomedicine and Practice. 2022, vol. 7, issue3, pp.266-273 12. Lutfillo Yorov, Mirjalol Djuraev, Nodir Raximov, Shakhnoza Shakhanova. Evaluation of the state of the immune status in patients with breast cancer with the determination of the effectiveness of neoadjuvant polychemotherapy. Journal of Biomedicine and Practice. 2022, vol. 7,issue 5, pp.211-216 13. Yunusova L. et al. Sonography and magnetic resonance tomography in monitoring of recurrent cysts lesions of the neck //Annals of Cancer Research and Therapy. – 2021. – Т. 29. – №. 2. – С. 131-134. 14. Yunusova L. et al. Magnetic resonance imaging in the diagnosis of cystic lesions of the neck //Annals of Cancer Research and Therapy. – 2021. – Т. 29. – №. 1. – С. 102-109.